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Background: Type 2 diabetes mellitus (T2D) is characterized by insulin resistance and progressive β-cell dysfunction. Although pharmacotherapy lowers glycemia, real-world escalation is common. The role of fruit in T2D remains debated. Objective: To evaluate short-term changes in fasting blood glucose, body weight, medication use, and patient-reported outcomes during a 7-day fruit and vegetable (FAV) diet among adults with T2D already following a whole-food plant-based diet (WFPBD). Methods: We conducted a retrospective analysis of 41 adults with T2D enrolled in an online diabetes reversal coaching program in September 2025. After ≥6 months on WFPBD, participants undertook a 7-day protocol of 3–4 fruit meals/day plus one mixed salad; grains, legumes, nuts, seeds, and cooked foods were excluded. Primary outcome was within-subject change in fasting blood glucose from day 0 to day 7; secondary outcomes included weight and medication changes. Analyses used paired tests with 95% CIs and effect sizes. Results: Mean fasting blood glucose decreased from 7.51 to 6.98 mmol/L (Δ −0.53 mmol/L, -7.1%). Mean body weight decreased from 71.73 to 70.21 kg (Δ −1.52 kg; −2.1%). Among 14 participants on glucose-lowering therapy, 4 (28.6%) reduced or discontinued medications, including 1 who discontinued insulin entirely. Reported adverse effects were mild and transient. Conclusions: In adults with T2D already adhering to WFPBD, a 7-day FAV diet was associated with short-term improvements in fasting blood glucose and body weight, with some reductions in medication use. These real-world findings are hypothesis-generating and support evaluation in controlled trials to determine efficacy, safety, and durability.

Background: The incidence of type-2 diabetes (T2D) has amplified worldwide, but significant improvement in overall health outcomes is not observed. A low carbohydrate diet is suggested as a nutritional strategy for diabetics to control blood glucose levels, but the outcomes are usually short-term and often unsustainable. Various studies have demonstrated sustained remission of T2D through lifestyle intervention including a whole food plant-based diet (WFPBD) with moderate glycemic load (MGL) combined with insulin sensitivity optimization (ISO) techniques such as intermittent fasting and fractional exercise. Methods: This article presents a case series of four diabetic patients who participated in an online 180-day diabetes reversal program in 2023. The intervention was a combination of MGL-oriented WFPBD along with ISO techniques including intermittent fasting and fractional exercise. The primary measures were changes in glycated hemoglobin (HbA1c), fasting blood glucose (FBG), body weight (BW), and body mass index (BMI). Results: The HbA1c values of the participants reduced from 13.3%, 12.5%, 9.5%, and 9.2% to less than 6.5% without any diabetes medications, and thus, they achieved diabetes remission as per the definition set by the American Diabetes Association. Significant improvements were also observed in FBG, BW, and BMI. All the participants remained in remission beyond the 12-month interval period with HbA1c below 6%.

Background: Type 2 diabetes mellitus is a chronic metabolic disorder characterized by insulin resistance, impaired glucose tolerance, and progressive β-cell dysfunction, resulting in persistent hyperglycemia. Traditionally, patients with diabetes are typically advised to limit fruit consumption to manage glucose levels. However, emerging research suggests that a higher fruit intake may play a role in preventing and reversing diabetes, due to their beneficial effects on insulin sensitivity, blood sugar regulation, and overall metabolic health. Objectives: This study aimed to evaluate the safety and efficacy of an all-fruit diet for type 2 diabetes patients. It focused on assessing the impact of fruit consumption on key biomarkers, such as blood sugar levels and body weight, while monitoring symptoms, participant adherence, and overall metabolic health during the diet regimen. Methods: A 9-day all-fruit diet study was conducted with 51 voluntary participants, all diagnosed with type 2 diabetes. Participants were instructed to consume 3 to 4 fruit-based meals daily, with each meal ranging from 500 grams to the point of satiation. Participants self-monitored their fruit consumption and reported changes in biomarkers to the study leads for analysis. Results: The study found that 94% of participants experienced weight loss and improved body mass index. Additionally, 88% of participants reported a decrease in fasting blood sugar levels. Many participants also reported feeling lighter and more energetic after completing the all-fruit diet regimen. Conclusions: The findings from the study highlight the significant benefits of an all-fruit diet. The diet proved both safe and effective in promoting weight loss, improving body mass index, and reducing fasting blood sugar levels.

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, impaired glucose tolerance, and progressive β-cell dysfunction, leading to persistent hyperglycemia. Traditionally, individuals with T2DM are advised to limit fruit consumption due to concerns over natural sugars. However, emerging evidence suggests that whole fruits may support metabolic health by improving insulin sensitivity and glycemic regulation. Objective: This study evaluated the short-term effects of an exclusively fruit-based diet on glycemic control, body weight, and overall metabolic well-being in individuals with T2DM. Methods: Thirty-two adults with type 2 diabetes participated in a 7-day all-fruit dietary intervention. Participants consumed 3–4 mono-meals of fruit daily, with individual meals consisting of 500 to 1000 grams of fruit. Self-reported data on dietary intake, symptoms, fasting blood glucose (FBG), and body weight (BW) were collected pre- and post-intervention for analysis. Results: The intervention resulted in a mean weight loss of 2.7 kg and an average decrease in FBG of 1.02 mmol/L. No serious adverse effects were reported. Conclusion: A short-term, all-fruit diet appears to be safe and effective in improving glycemic control and reducing body weight in people with T2DM. Further research with larger sample sizes and controlled conditions is warranted to validate these findings and assess long-term outcomes.

Abstract: Type 2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia. T2D may lead to health complications such as retinal damage, chronic kidney disease, peripheral neuropathy, systemic hypertension, and coronary heart disease. This case report presents the complete reversal of T2D in a newly diagnosed patient after initiation of a whole food plant-based diet. He was able to reverse diabetes and maintain normal blood glucose readings without any pharmacological treatment.

Background: The incidence of diabetes has amplified worldwide, but health outcomes have not improved significantly. Anti-hyperglycemic medications are often accompanied by weight gain, hypoglycemia, and risk of cardiovascular events. Most diabetics are suggested a “low carb diet” as a nutritional strategy but the results short-termed and often unsustainable in most cases. Aims: This case report depicts the effectiveness of a personalized nutritional intervention program focused on Whole Food Plant Based Diet (WFPBD) and Intermittent Fasting (IF) in reducing blood glucose, body weight, waist circumference, without any pharmacological treatment. Methods: We present a case of a personalized nutritional intervention program of a 47-year-old diabetic female, weighing 86 kgs, measuring 168 cm (BMI 30.5), with waist circumference of 43 inches. Her pre-intervention glycated hemoglobin (HbA1c) was 12.5%, post prandial glucose (PPG) was 342 mg/dl, and fasting blood glucose (FBG) was 250 mg/dl. Besides following a WFPBD, the patient was advised to do intermittent fasts of 14 hours, starting from about 6 pm in the evening and extending till about 8 am the next morning. The primary measures were changes in HbA1c, fasting and postprandial glucose levels, body weight, waist circumference, and BMI. Results: Nutritional intervention brought substantial improvements in several health parameters of the patient. Post-intervention, the patient was able to achieve an HbA1c of 6.40%, average FBG of 113 mg/dl, average PPG of 127 mg/dl, body weight of 74 kgs, BMI of 26.2, and waist circumference of 37 inches. Conclusions: The results suggest that a personalized dietary modification program combining WFPBD and IF can significantly improve metabolic health and potentially reverse T2D without the need for pharmacological treatment.

Abstract: The consumption of 100% fruit juice has been a subject of controversy due to abundance of free sugars leading to inconsistent dietary guidelines. This study aimed to verify the hypothesis if eating whole fruit scores better than drinking fruit juices in terms of glycemic control.15 type-2 diabetic patients volunteered from author’s online Diabetes Reversal Program to participate in the observational study. The relative effect of consumption of 300-ml orange FJ and 300-gram whole orange fruit on glycemic control was compared to verify the hypothesis. The findings of the study suggested that the consumption of oranges (whether juiced or eaten whole) is safe and well tolerable for diabetics and does not substantially raise the blood glucose levels in the average diabetic, however, individualized dietary modification would be the optimal practice to achieve desired health outcomes.

Abstract: Type-2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia. T2D may lead to health complications such as retinal damage, chronic kidney disease, peripheral neuropathy, systemic hypertension, and coronary heart disease. In the present case report, we observed remission of T2D in a newly diagnosed aged patient after initiation of a whole food plant-based diet. The patient was able to achieve normal blood glucose readings without any pharmacological treatment. HbA1c lowered from 13.30% to 5.6% after 12 weeks of nutritional intervention.